Tag Archives: prostate cancer

Tomatoes, Lycopene and Prostate Cancer

TomatoI had the opportunity to write an article for this month’s issue of the Natural Medicine Journal about the connection between Lycopene and prevention of Prostate cancer. This is following results of the Health Professionals Follow-up Study (HPFS) published in the Journal of the National Cancer Institute earlier this year. The HPFS is an ongoing study of over 50,000 men who were between the ages of 40 and 75 at the beginning of the study in 1986. After nearly 30 years of following the dietary habits and health status of these men, they have found a distinct protective effect of consumption of foods that are high in lycopene.

Lycopene is a carotenoid, a class of compounds that often give plants a yellow, orange, or red color. The foods that are most common in the Western diet that are highest in lycopene are tomatoes, pink grapefruit, and watermelon. Processed tomato foods such as tomato paste and sauce are particularly high in lycopene because it becomes concentrated. Lycopene has the most potent antioxidant activity of all the carotenoids, and there have been many studies over the past several decades that have demonstrated the ability of lycopene to detoxify, prevent cell damage, and initiate death of cancer cells.

This current study is of particular interest to us because, from a prevention standpoint, it looks at whole foods instead of supplements, and it gives us a long-term look at a large number human subjects rather than animal or in-vitro models. The most significant finding in this study is that “men with the highest (cumulative) intake were half as likely to develop lethal prostate cancer compared with those with the lowest intake”. That is, the men who started eating foods with the highest amount of lycopene earliest in life were least likely to die of prostate cancer.

It is also important to note that these men who fared the best in the study seemed to have better habits overall. Those with the highest lycopene consumption “also consumed less alcohol, coffee and all three types of fats and slightly more fruits, vegetables, and dietary fiber”. Diets rich in fruits and vegetables have also been generally found to be protective against cancers and prostate cancer specifically.

What is the take home message from this study? The best way to take care of your prostate is to eat fruits and vegetables, particularly those high in lycopene, and start early–the impact you will have will be so much more powerful now than making changes once a problem arises.

If you would like to see the full article in the Natural Medicine Journal Click Here

Source: Zu, Ke et al. Dietary Lycopene, Angiogenesis, and Prostate Cancer: A Prospective Study in the Prostate-Specific Antigen Era. Journal of the National Cancer Institute. 2014. 106 (2).